81 Artículos relativos a Nivel sin Efectos Adversos Observados

• Application of QSARs in risk management of existing chemicals.
  Publicado en SAR QSAR Environ Res
• Utilizing uncertainty factors in minimal risk levels derivation.
  Publicado en Regul Toxicol Pharmacol
• Genotoxicity and twenty-eight-day subchronic toxicity studies on tertiary amyl methyl ether.
  Publicado en J Appl Toxicol
• Safety evaluation of beta-glucanase derived from Trichoderma reesei: summary of toxicological data.
  Publicado en Food Chem Toxicol
• Wplyw zanieczyszczenia wód substancjami powierzchniowo-czynnymi i srodkami ochrony roslin na organizmy wodne.
  Publicado en Rocz Panstw Zakl Hig
• Fundamentals and possibilities of classification of occupational substances as developmental toxicants.
  Publicado en Int Arch Occup Environ Health
• Correlation of synergistic cytotoxic effects of environmental chemicals in human fibroblasts with their lipophilicity.
  Publicado en Chemosphere
• Embryotoxicity induced by alkylating agents: 9. Low dose prenatal-toxic risk estimation of ethylmethanesulfonate based on no-observed-adverse-effect-level risk factor approach, dose-response relationships, and molecular dosimetry.
  Publicado en Teratog Carcinog Mutagen
• The effects of subchronic chlorate exposure in Sprague-Dawley rats.
  Publicado en Drug Chem Toxicol
• In vitro assessment of the effect of methanol and the metabolite, formic acid, on embryonic development of the rat.
  Publicado en Teratology
• Biologically bounded risk assessment for receptor-mediated nongenotoxic carcinogens.
  Publicado en Regul Toxicol Pharmacol
• Which multiple of a safe body dose derived on the basis of default factors would probably be unsafe?.
  Publicado en Regul Toxicol Pharmacol
• The use of an additional safety or uncertainty factor for nature of toxicity in the estimation of acceptable daily intake and tolerable daily intake values.
  Publicado en Regul Toxicol Pharmacol
• A human health risk assessment of boron (boric acid and borax) in drinking water.
  Publicado en Regul Toxicol Pharmacol
• Thresholds in chemical carcinogenesis.
  Publicado en Regul Toxicol Pharmacol
• Developmental toxicity of inhaled N-methylformamide in the rat.
  Publicado en Fundam Appl Toxicol
• Need to revise the national drinking water regulation for copper.
  Publicado en Regul Toxicol Pharmacol
• Neurotoxicity modeling for risk assessment.
  Publicado en Regul Toxicol Pharmacol
• Tissue dosimetry, pharmacokinetic modeling, and interspecies scaling factors.
  Publicado en Risk Anal
• Reanalysis of dose-response data from the Iraqi methylmercury poisoning episode.
  Publicado en Risk Anal
• Determination of a no-observed-effect level for developmental toxicity of ethylene glycol administered by gavage to CD rats and CD-1 mice.
  Publicado en Fundam Appl Toxicol
• Studies on the prenatal toxicity of 3-methyl-1-butanol and 2-methyl-1-propanol in rats and rabbits following inhalation exposure.
  Publicado en Fundam Appl Toxicol
• Evaluation of the developmental toxicity of ethylene glycol aerosol in CD-1 mice by nose-only exposure.
  Publicado en Fundam Appl Toxicol
• Effects of propylene oxide on nasal epithelial cell proliferation in F344 rats.
  Publicado en Fundam Appl Toxicol
• Identifying the "residue of toxicological concern"--bioavailability and bioactivity testing.
  Publicado en Drug Metab Rev
• Alternatives for a risk assessment on chronic noncancer effects from oral exposure to trichloroethylene.
  Publicado en Regul Toxicol Pharmacol
• Quantalization of continuous data for benchmark dose estimation.
  Publicado en Regul Toxicol Pharmacol
• Developmental toxicity of Exell, a surfactant mixture, in rats and rabbits.
  Publicado en Drug Chem Toxicol
• A semiparametric approach to risk assessment for quantitative outcomes.
  Publicado en Risk Anal
• Establishing tolerable dungeness crab (Cancer magister) and razor clam (Siliqua patula) domoic acid contaminant levels.
  Publicado en Environ Health Perspect
• Toxicity of 2,2',4,4',5,5'-hexachlorobiphenyl in rats: effects following 90-day oral exposure.
  Publicado en J Appl Toxicol
• Expanding the reference dose concept to incorporate and optimize beneficial effects while preventing toxic responses from nonessential toxicants.
  Publicado en Regul Toxicol Pharmacol
• Comparative subchronic studies on 2,4-dichlorophenoxyacetic acid, amine, and ester in rats.
  Publicado en Fundam Appl Toxicol
• Benchmark dose analysis of developmental toxicity in rats exposed to boric acid.
  Publicado en Fundam Appl Toxicol
• Developmental toxicity NOAEL and postnatal recovery in rats fed boric acid during gestation.
  Publicado en Fundam Appl Toxicol
• Methods of risk assessment.
  Publicado en Sci Total Environ
• Ecological hazard assessment of dioxins: hazards to organisms at different levels of aquatic food webs (fish-eating birds and mammals, fish and invertebrates).
  Publicado en Sci Total Environ
• A 90-day chloroform inhalation study in female and male B6C3F1 mice: implications for cancer risk assessment.
  Publicado en Fundam Appl Toxicol
• Thirteen-week inhalation toxicity of 2- and 4-chloronitrobenzene in F344/N rats and B6C3F1 mice.
  Publicado en Fundam Appl Toxicol
• Evaluation of the developmental and reproductive toxicity of chlorpyrifos in the rat.
  Publicado en Fundam Appl Toxicol
• Comparative subchronic and chronic dietary toxicity studies on 2,4-dichlorophenoxyacetic acid, amine, and ester in the dog.
  Publicado en Fundam Appl Toxicol
• Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on influenza virus host resistance in mice.
  Publicado en Fundam Appl Toxicol
• Biologically based, quantitative risk assessment of neurotoxicants.
  Publicado en Fundam Appl Toxicol
• An attempt to define a just detectable effect for airborne chemicals on the respiratory tract in mice.
  Publicado en Arch Toxicol
• Further insights into the influence of L-cysteine on the oxidation chemistry of dopamine: reaction pathways of potential relevance to Parkinson's disease.
  Publicado en Chem Res Toxicol
• Re: The use of uncertainty factors in estimating health risks.
  Publicado en Fundam Appl Toxicol
• Embryotoxicity study of monomeric 4,4'-methylenediphenyl diisocyanate (MDI) aerosol after inhalation exposure in Wistar rats.
  Publicado en Fundam Appl Toxicol
• Use of lung toxicity and lung particle clearance to estimate the maximum tolerated dose (MTD) for a fiber glass chronic inhalation study in the rat.
  Publicado en Fundam Appl Toxicol
• Subchronic toxicity of 4-vinylcyclohexene in rats and mice by inhalation exposure.
  Publicado en Fundam Appl Toxicol
• Two-generation reproduction study of sulfur mustard in rats.
  Publicado en Reprod Toxicol
• Effect of day of exposure on the developmental toxicity of manganese in mice.
  Publicado en Vet Hum Toxicol
• Cardiac sensitization thresholds of halon replacement chemicals predicted in humans by physiologically-based pharmacokinetic modeling.
  Publicado en Risk Anal
• Application of a biologically-based RFD estimation method to tetrachlorodibenzo-p-dioxin (TCDD) mediated immune suppression and enzyme induction.
  Publicado en Risk Anal
• No-effect concentration as a basis for ecological risk assessment.
  Publicado en Risk Anal
• Hepatocarcinogenic potential of di(2-ethylhexyl)phthalate in rodents and its implications on human risk.
  Publicado en Crit Rev Toxicol
• A probabilistic model for deriving soil quality criteria based on secondary poisoning of top predators. II. Calculations for dichlorodiphenyltrichloroethane (DDT) and cadmium.
  Publicado en Ecotoxicol Environ Saf
• A probabilistic model for deriving soil quality criteria based on secondary poisoning of top predators. I. Model description and uncertainty analysis.
  Publicado en Ecotoxicol Environ Saf
• Toxicity studies of epichlorohydrin in Sprague-Dawley rats.
  Publicado en Drug Chem Toxicol
• Reproductive toxicity evaluation of methylethyl ketoxime by gavage in CD rats.
  Publicado en Fundam Appl Toxicol
• Probabilistic assessment of health risks of methylmercury from burning coal.
  Publicado en Neurotoxicology
• Do historic studies of fish consumers support the widely accepted LOEL for methylmercury in adults.
  Publicado en Neurotoxicology
• Risk assessment of mercury exposure through fish consumption by the riverside people in the Madeira Basin, Amazon, 1991.
  Publicado en Neurotoxicology
• Sensory and cognitive effects of developmental methylmercury exposure in monkeys, and a comparison to effects in rodents.
  Publicado en Neurotoxicology
• Occupational exposure.
  Publicado en Food Chem Toxicol
• Assessment of potential health risks associated with ingesting heavy metals in fish collected from a hazardous-waste contaminated wetland in Louisiana, USA.
  Publicado en Rev Environ Health
• Copper transfer and influence on a marine food chain.
  Publicado en Bull Environ Contam Toxicol
• Developmental toxic effects of fusaric acid in CD1 mice.
  Publicado en Bull Environ Contam Toxicol
• Uncertainty in estimated half-lives of PCBS in humans: impact on exposure assessment.
  Publicado en Sci Total Environ
• A screening method for occupational reproductive health risk.
  Publicado en Am Ind Hyg Assoc J
• Developmental toxicity evaluation of sodium fluoride administered to rats and rabbits in drinking water.
  Publicado en Fundam Appl Toxicol
• Case studies defining non-toxic and toxic dose of pharmaceuticals.
  Publicado en J Toxicol Sci
• The role of toxicology in the evaluation of new agrochemicals.
  Publicado en J Environ Sci Health B
• Reproductive and developmental toxicity study of a new antineoplastic agent, S-1 (IV)--Perinatal and postnatal study in rats by oral administration.
  Publicado en J Toxicol Sci
• Reproductive and developmental toxicity study of a new antineoplastic agent, S-1 (III)--Teratological study in rabbits by oral administration.
  Publicado en J Toxicol Sci
• Reproductive and developmental toxicity study of a new antineoplastic agent, S-1 (II)--Teratological study in rats by oral administration.
  Publicado en J Toxicol Sci
• Reproductive and developmental toxicity study of a new antineoplastic agent, S-1 (I)--Fertility study in rats by oral administration.
  Publicado en J Toxicol Sci
• A 26-week oral repeated dose toxicity study of a new antineoplastic agent S-1 in rats.
  Publicado en J Toxicol Sci
• A 13-week oral repeated dose toxicity study of a new antineoplastic agent S-1 in rats.
  Publicado en J Toxicol Sci
• Subchronic toxicity evaluation of lewisite in rats.
  Publicado en J Toxicol Environ Health
• Maternal reproductive effects of oral salicylic acid in Sprague-Dawley rats.
  Publicado en Toxicol Lett
• Qualitative investigation of uptake of fine particle size microcrystalline cellulose following oral administration in rats.
  Publicado en J Anat