2,223 Artículos relativos a Farmacocinética

• Definition and determination of important pharmacokinetic parameters for dosage regimen (one compartment model).
  Publicado en Eur J Toxicol Hyg Environ
• Pharmacokinetic properties and their relation to certain physicochemical properties.
  Publicado en Eur J Toxicol Hyg Environ
• Empirical equation for pharmacokinetic analysis of drug serum levels after oral application.
  Publicado en Antimicrob Agents Chemother
• The effects of extremes of age on drug action.
  Publicado en Methods Find Exp Clin Pharmacol
• Direct linear plotting method for estimation of pharmacokinetic parameters.
  Publicado en J Pharm Sci
• Transport in quantitative structure-activity relationships. VI: Relationship between transport rate constants and partition coefficients.
  Publicado en J Pharm Sci
• Drug demethylation by calcium-aggregated microsomes prepared from rabbit organs.
  Publicado en Ann Univ Mariae Curie Sklodowska [Med]
• KMCP: a kinetics-management computer package in clinical pharmacology application.
  Publicado en Gaoxiong Yi Xue Ke Xue Za Zhi
• A demonstration of pharmacokinetics and physiological modelling using a microcomputer for data capture and analysis.
  Publicado en Comput Appl Biosci
• Constant pharmacologic effect and chronopharmacology: theoretical aspects.
  Publicado en Chronobiol Int
• In vivo metabolism and disposition of drugs by aquatic species.
  Publicado en Vet Hum Toxicol
• Solving algebraic equations on a microcomputer.
  Publicado en Comput Appl Biosci
• Topical ocular drug delivery: recent developments and future challenges.
  Publicado en J Ocul Pharmacol
• Effects of estrone on the biliary excretion of xenobiotics.
  Publicado en Pol J Pharmacol Pharm
• Drug disposition in cystic fibrosis: progress in understanding pathophysiology and pharmacokinetics.
  Publicado en Pediatr Infect Dis J
• Physiology of lactation and factors affecting lactation.
  Publicado en Obstet Gynecol Clin North Am
• The influence of nutrition on the systemic availability of drugs. Part II: Drug metabolism and renal excretion.
  Publicado en Klin Wochenschr
• An equation for the systemic availability of drugs undergoing simultaneous enterohepatic cycling, first-pass metabolism, and intestinal elimination.
  Publicado en Pharm Res
• Kinetic-effect models and their applications.
  Publicado en Pharm Res
• Implications of the neglect of stereochemistry in pharmacokinetics and clinical pharmacology.
  Publicado en Drug Intell Clin Pharm
• Pharmacotherapy of pediatric lung disease: differences between children and adults.
  Publicado en Clin Chest Med
• Assessment of variance in bioavailability studies: comments on the article by McNamara et al.
  Publicado en Pharm Res
• The lipoidal permeability barriers of the skin and alimentary tract.
  Publicado en Pharm Res
• Drug release from tablets containing cellulose acetate phthalate as an additive or enteric-coating material.
  Publicado en Pharm Res
• Application of moment analysis to nonlinear drug disposition described by the Michaelis-Menten equation.
  Publicado en Pharm Res
• Subcellular distribution of basic drugs accumulated in the isolated perfused lung.
  Publicado en Pharm Res
• Targeted drug delivery--some pharmacokinetic considerations.
  Publicado en Pharm Res
• Applying pharmacokinetic principles to the management of drug poisoning.
  Publicado en Pediatr Ann
• Recommendations for controlling the effects of nutrition during assessment of the systemic availability of drugs.
  Publicado en Klin Wochenschr
• Un programme pour les décroissances biexponentielles.
  Publicado en J Toxicol Clin Exp
• Pharmacokinetic/pharmacodynamic modeling: what it is!.
  Publicado en J Pharmacokinet Biopharm
• Estimates of the population pharmacokinetic parameters and performance of Bayesian feedback: a sensitivity analysis.
  Publicado en J Pharmacokinet Biopharm
• Therapeutic drug monitoring in ambulatory pediatrics.
  Publicado en J Pediatr Health Care
• Controversy. II: Bioequivalence as an indicator of therapeutic equivalence: modeling the theoretic influence of bioinequivalence on single-dose drug effect.
  Publicado en J Clin Pharmacol
• Osobennosti deistviia lekarstvennykh veshchestv, metaboliziruiushchikhsia v pecheni, pri éksperimental'noi splenéktomii.
  Publicado en Farmakol Toksikol
• A variable reabsorption time-delay model for pharmacokinetics of drugs.
  Publicado en Eur J Drug Metab Pharmacokinet
• Pharmacokinetic considerations in treatment of severe heart disease.
  Publicado en East Afr Med J
• Criteria for the acceptability of experimental evidence for the enantiomeric composition of xenobiotics and their metabolites.
  Publicado en Drug Metab Dispos
• Effect of maturation on drug disposition in pediatric patients.
  Publicado en Clin Pharm
• The clinical investigation of drugs for use by the elderly: Food and Drug guidelines.
  Publicado en Clin Pharmacol Ther
• Intranasal drug delivery for systemic medications.
  Publicado en Crit Rev Ther Drug Carrier Syst
• Advances in pediatric pharmacology and toxicology.
  Publicado en Adv Pediatr
• Strain independent elevation of hepatic mono-oxygenase enzymes in female mice.
  Publicado en Xenobiotica
• Effects of picloram on xenobiotic biotransformation in rat liver.
  Publicado en Xenobiotica
• Comparability of in vitro and in vivo methods for the determination of alterations in drug metabolism.
  Publicado en Toxicol Lett
• Insuffisance rénale et métabolisme des médicaments.
  Publicado en Therapie
• Particularitati farmacocinetice în perioada graviditatii.
  Publicado en Rev Med Chir Soc Med Nat Iasi
• Chronopharmacology: a new perspective in pharmacology.
  Publicado en Pol J Pharmacol Pharm
• Interakcje leków.
  Publicado en Pieleg Polozna
• Site dependence of drug concentrations in postmortem blood--a case study.
  Publicado en J Anal Toxicol
• Mean residence time in peripheral tissue.
  Publicado en J Pharmacokinet Biopharm
• Effect of a diffusional barrier to a metabolite across hepatocytes on its kinetics in "enzyme-distributed" models: a computer-aided simulation study.
  Publicado en J Pharmacokinet Biopharm
• Ethics of drug studies in infants: how many samples are required for accurate estimation of pharmacokinetic parameters in neonates?.
  Publicado en J Pediatr
• Drug absorption.
  Publicado en J Clin Pharmacol
• Determination of the in vivo Km and Vmax of a drug with tracer studies.
  Publicado en J Clin Pharmacol
• In consideration of active metabolites.
  Publicado en J Clin Pharmacol
• Drug absorption rate: a critical component of bioequivalence assessment in psychopharmacology.
  Publicado en J Clin Pharmacol
• The pathobiologic significance of intracellular drug storage: clear cytoplasmic vacuoles.
  Publicado en Hum Pathol
• Comment: ambulatory kinetic monitoring.
  Publicado en Drug Intell Clin Pharm
• Influence of obesity on drug disposition.
  Publicado en Clin Pharm
• Chronopharmacology and chronotherapeutics: definitions and concepts.
  Publicado en Chronobiol Int
• Transdermal drug delivery: problems and possibilities.
  Publicado en Crit Rev Ther Drug Carrier Syst
• Neuropharmacological and neurochemical properties of N-(2-cyanoethyl)-2-phenylethylamine, a prodrug of 2-phenylethylamine.
  Publicado en Br J Pharmacol
• Pharmacokinetics and tolerance of desciclovir, a prodrug of acyclovir, in healthy human volunteers.
  Publicado en Antimicrob Agents Chemother
• Model'nye i model'no-nezavisimye metody opisaniia farmakokinetiki: preimushchestva, nedostatki i vzaimosviaz'.
  Publicado en Antibiot Med Biotekhnol
• Osnovnye étapy issledovaniia farmakokinetiki substantsii novykh preparatov.
  Publicado en Antibiot Med Biotekhnol
• Posologie des médicaments chez le patient obèse.
  Publicado en Ther Umsch
• Drug plasma protein binding and pharmacokinetics.
  Publicado en Sheng Li Ke Xue Jin Zhan
• Eine neue Versuchsanordnung zur in-vitro-Beurteilung der Wirkstoffresorption aus topischen Arzneiformen. 1. Mitteilung: Versuchsanordnung und Modellrechnungen.
  Publicado en Pharmazie
• Pharmakokinetic und -dynamik unter dem Einfluss ionisierender Strahlen.
  Publicado en Pharmazie
• Extended least squares (ELS) for pharmacokinetic models.
  Publicado en J Pharm Sci
• Analysis of structural requirements for the absorption of drugs and macromolecules from the nasal cavity.
  Publicado en J Pharm Sci
• Kinetics of drug action in disease states. XXI. Relationship between drug infusion rate and dose required to produce a pharmacologic effect.
  Publicado en J Pharm Sci
• The use and abuse of models.
  Publicado en J Pharmacokinet Biopharm
• Theorems and implications of a model-independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. IV. Exact relationship between the terminal log-linear slope parameter beta and drug clearance.
  Publicado en J Pharmacokinet Biopharm
• Theorems and implications of a model-independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. III. Peripheral bioavailability and distribution time concepts applied to the evaluation of distribution kinetics.
  Publicado en J Pharmacokinet Biopharm
• Area method for the estimation of partition coefficients for physiological pharmacokinetic models.
  Publicado en J Pharmacokinet Biopharm
• A minimax approach to the single-point method of drug dosing.
  Publicado en J Pharmacokinet Biopharm
• Problemi di farmacocinetica in gravidanza.
  Publicado en Clin Ter
• Drug therapy in the elderly: special considerations.
  Publicado en Geriatrics
• Opredelenie soderzhaniia lekarstvennykh veshchestv v sliune v klinicheskikh i éksperimental'nykh issledovaniiakh farmakokinetiki.
  Publicado en Farmakol Toksikol
• Proton-motive-force-driven formation of CO from CO2 and H2 in methanogenic bacteria.
  Publicado en Eur J Biochem
• A simplex procedure for fitting nonlinear pharmacokinetic models.
  Publicado en Comput Biol Med
• An evaluation of population pharmacokinetics in therapeutic trials. Part II. Detection of a drug-drug interaction.
  Publicado en Clin Pharmacol Ther
• Bias in pharmacokinetics and clinical pharmacology.
  Publicado en Clin Pharmacol Ther
• Prediction of steady-state bioequivalence relationships using single dose data I-linear kinetics.
  Publicado en Biopharm Drug Dispos
• Giving drugs per rectum for systemic effect.
  Publicado en Arch Dis Child
• Pharmacokinetic perfusion model of presystemic metabolism with renal clearance.
  Publicado en Zhongguo Yao Li Xue Bao
• Relations allométriques en pharmacocinétique. Influence sur la pharmacodynamie (de la souris à l'éléphant, sans oublier l'homme).
  Publicado en Therapie
• Urinary 6-beta-OH-cortisol and paracetamol metabolites as a probe for assessing oxidation and conjugation of chemicals in humans.
  Publicado en Pharmacol Res Commun
• On the difficulties of fitting the double Michaelis-Menten equation to kinetic data.
  Publicado en J Theor Biol
• Clinical pharmacology in criminal cases: discussion paper.
  Publicado en J R Soc Med
• Studies on drug absorption from oral cavity. II. Influence of the unstirred water layer on absorption from hamster cheek pouch in vitro and in vivo.
  Publicado en J Pharmacobiodyn
• Proceedings of the 18th Symposium on Drug Metabolism and Action. Toyama.
  Publicado en J Pharmacobiodyn
• Principles of drug therapy.
  Publicado en J Enterostomal Ther
• Biliary excretion.
  Publicado en J Clin Pharmacol
• Determination of metabolite pharmacokinetics for orally administered prodrugs.
  Publicado en Drug Metab Dispos
• Microcomputer-based programs for calculating mean and variance residence time by the method of prospective areas.
  Publicado en Comput Methods Programs Biomed
• Kinetika biologickej ucinnosti xenobiotík.
  Publicado en Cesk Farm
• Simultaneous modeling of pharmacokinetics and pharmacodynamics: an improved algorithm.
  Publicado en Comput Appl Biosci